Destruction of Mouse Skin Sebaceous Glands by Actinomycin D*
نویسندگان
چکیده
منابع مشابه
Sebaceous Glands and Experimental Skin Carcinogenesis in Mice*
The fluorescence microscopic study (5) ot~ the absorption by mouse skin of methylcholanthrene in benzene has shown that a large portion of the carcinogen goes immediately to the sebaceous glands, where it is found dissolved in the lipid droplets within /he gland cells. Another portion is absorbed by the keratinized layer of the epidermal epithelium, where it is dissolved in the free intracellul...
متن کاملSebaceous glands in the esophagus.
We report a case of sebaceous glands in the esophagus diagnosed by endoscopic biopsy. The patient was a 47-year-old Korean man presented with postprandial pain of several months duration. An endoscopic examination disclosed an early gastric carcinoma in the gastric antrum and a 0.4 x 0.4 cm sized irregular lobulated nodule in the middle esophagus. Microscopically, the lobule was proven to be se...
متن کاملTumor inhibition, persistence, and binding of actinomycin D in mouse skin.
Actinomycin D (AMD) inhibits tumor induction by 63% when applied as late as 31 days after single treatment with 7,12-dimethylbenz [a] anthracene and 90 days prior to repeated treatment with the tumor-promoting agent phorbol myristate acetate in two-stage carcinogenesis on mouse skin. Inhibition was 61% when AMD was applied 90 days after 7,12-dimethylbenz [a] anthracene and 14 days prior to phor...
متن کاملSuppression of erythropoiesis by actinomycin D. I. Evolutional change of hemopoiesis by actinomycin D.
For the purpose of revealing whether the sensitivity of the erythropoiesis to actinomycin D (AMD) differs among different animal species, and to see the acting site of AMD on erythroid cell specialization stage, the author observed the hourly change of the blood cell counts and bone marrow cells after AMD administration to mice, rats and rabbits, and obtained the following results: 1. The data ...
متن کاملInhibition of Mycoplasma pneumoniae by actinomycin D.
Growth of Mycoplasma pneumoniae was completely prevented by 0.06 mug of actinomycin D/ml, and 0.00375 mug/ml caused 90% inhibition. It thus appears that M. pneumoniae is more susceptible to actinomycin D than previously reported. Low concentrations (0.019 mug/ml) of the antibiotic primarily inhibited ribonucleic acid synthesis and high concentrations (20 mug/ml) inhibited both ribonucleic and d...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 1967
ISSN: 0022-202X
DOI: 10.1038/jid.1967.142